|
KMID : 0356619930080030347
|
|
Journal of Korean Society of Endocrinology
1993 Volume.8 No. 3 p.347 ~ p.350
|
|
|
The Effects of Granulogyte Colony Stimulating Factor(G-CSF) in a Patient with Propylthiouracil-Induced Agranulocytosis
|
|
유광현
손성식/송승렬/박명선/이용구/조정구
|
|
|
Abstract
|
|
|
ABSTRACT
@EN Agranulocytosis represents a life-threatening complication of antithyroid therapy, occurring in 0.1% to 1% of patients. Course and duration of agranulocytosis may be highly variable. Recently, recombinant human granulocyte-macrophage colony
stimulating factor (rhGH-CSF) and granulocyte colony stimulating factor (rhG-CSF) have proved useful in the treatment of idiopathic aplastic anemia, idiopathic neutropenia, and chemotherapy-associated agranulocytosis. That G-CSF might also be
useful in
drug-induced allergic-toxic agranulocytosis.
We experienced successful rhG-CSF treatment of a 25-year-old woman who had propylthiouracil-induced agrnulocytosis. The availability of G-CSF may help to shorten the course of agranulocytosis and to reduce its fatality rate (J Kor Soc Endocrinol
8:347~350, 1993).
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|